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News from ������� Langone Health

How To Stay Cool And Safe In A Heat Wave. (New York Times)

(6/19) Extreme heat is increasingly prevalent globally, posing risks such as heat stroke and heat exhaustion; Adriana Quinones-Camacho, MD, associate professor, Department of Medicine, the Leon H. Charney Division of Cardiology, chief, Medicine, Tisch Hospital, advised that staying hydrated is crucial, recommending increased water intake and electrolyte drinks like Gatorade to counteract sweat-induced electrolyte loss, with a reminder that hydration needs vary individually.

Recovering From Surgery Isn’t Easy. Exercising In The Water Can Help. (Washington Post)

The (6/22) Aquatic therapy offers a beneficial alternative to traditional land-based exercise for post-surgery recovery, with �����о��� Langone Health pediatric orthopedic surgeon, Mara Karamitopoulos, MD, the Elly and Stephen Hammerman Clinical Professor of Pediatric Surgery, Department of Orthopedic Surgery, and chief, Division of Pediatric Orthopedic Surgery, saying, “Water therapy is sometimes even more effective than land-based therapy because surgery patients don’t have the same range of motion and mobility,” while the natural buoyancy and resistance of water aid in reducing joint pressure and building endurance.

What You Really Need To Be Doing To Stay Fit At Every Age – And An Exercise Rule For ‘Weekend Warriors’. (New York Post)

The (6/23) Natasha N. Desai, MD, clinical assistant professor, Department of Orthopedic Surgery, Division of Sports Medicine, Women’s Sports Medicine Center, provides fitness advice for different age groups, emphasizing that exercise priorities evolve over time; she advises starting slow, varying routines, and incorporating strength and balance training to prevent injuries and maintain health, particularly for those over 35 who should consider a cardiology evaluation before starting a fitness regimen, while older adults should focus on resistance and balance training to avoid falls and maintain bone health.

Eli Lilly’s Obesity Pill Appears To Work As Well As Injected GLP-1s. (Wired)

(6/21) Eli Lilly’s experimental daily anti-obesity pill, orforglipron, demonstrated comparable efficacy in weight loss and blood sugar reduction to injectable GLP-1 drugs like Ozempic in a Phase 3 trial presented at the American Diabetes Association meeting and published in the New England Journal of Medicine; Priya Jaisinghani, MD, clinical assistant professor, Department of Medicine, the Holman Division of Endocrinology, Diabetes, & Metabolism, said, “With orforglipron offering additional advantages such as the elimination of strict pre-dosing requirements, potential lower cost, and easier storage, it will be important to see whether these features lead to even greater adherence.”

When Will Genetically Modifying Our Children Go Mainstream? (Gizmodo)

(6/22) Scientific organizations, including the International Society for Cell and Gene Therapy, are advocating for a 10-year moratorium on human heritable germline editing using CRISPR, citing safety concerns and the need for stronger regulations; Art Caplan, PhD, the Drs. William F. and Virginia Connolly Mitty Professor of Bioethics, Department of Population Health, Division of Medical Ethics, discussed historical and ethical considerations, emphasizing that while genetic engineering of children is likely inevitable, the current tools are too crude for safe application in the next decade.

Treatment Options And AE Considerations In First-Line EGFR+ NSCLC. (Cancer Network)

(6/20) At the European Lung Cancer Conference 2025, experts discussed the FLAURA2 and MARIPOSA trials, which compare osimertinib and the combination of amivantamab and lazertinib for EGFR-mutated non-small cell lung cancer, with results showing improved overall survival for the MARIPOSA regimen; Vamsidhar Velcheti, MD, professor, Department of Medicine, Division of Hematology and Medical Oncology, Perlmutter Cancer Center, said the second option for NCCN guidelines is reasonable, and emphasized the need for more education for oncology nurses.

The Overlooked Role Of Obstructive Sleep Apnea In Alzheimer Pathogenesis. (Neurology Live)

(6/20) At the SLEEP Annual Meeting in Seattle, Ominigho Michael Bubu, MD, PhD, associate professor, Departments of Psychiatry, Department of Neurology, Department of Population Health, presented on the impact of obstructive sleep apnea (OSA) on neurodegenerative diseases, particularly Alzheimer’s Disease, and discussed how OSA mechanisms like hypoxia and sleep fragmentation may accelerate AD risk, with disparities noted across racial and gender lines. 

Youth OD Deaths Involving Only Synthetic Opioids Rose 168% In 5 Years. (Healio)

(6/20) Opioid overdose deaths among youth aged 15 to 24 rose 52% from 2018 to 2022, with synthetic opioids alone responsible for one-third of the 2022 deaths, as reported in Pediatrics; Megan Miller, MPH, research coordinator, Center for Opioid Epidemiology and Policy, said, “We know that youth overdose deaths have stayed alarmingly high in recent years, with notable differences across sociodemographic groups,” and emphasized the need for pediatricians to educate on fentanyl risks, distribute harm-reduction tools like naloxone, and advocate for youth-focused addiction treatment, noting a 168% increase in deaths caused by synthetic opioids alone from 2018 to 2022.

What Might Be Going On If Rest Makes Your Back Pain Worse. (SELF Magazine)

(6/20) Prolonged rest can exacerbate back pain, particularly in cases of chronic inflammatory conditions like axial spondyloarthritis, where movement can alleviate stiffness by reducing the load on injured joints, according to Salvador E. Portugal, MBA, DO, assistant professor, Department of Rehabilitation Medicine, who advises rest for acute injuries like herniated discs but acknowledges the benefits of physical activity for chronic conditions.

Age-Friendly ERs Are Good Medicine. (Warren (OH) Tribune Chronicle)

The (6/20) Ula Hwang, MD, MPH, professor, the Ronald O. Perelman Department of Emergency Medicine, and Population Health, discussed the importance of age-friendly emergency care, saying that older adults, who account for 21% of emergency department visits, can benefit from specialized protocols and physical adaptations to prevent issues like delirium, with age-friendly departments focusing on the “4Ms” model, which includes evaluating medication and cognitive issues, while also considering what matters most to patients.

Cannabis Use In Older Adults: 7% Of Seniors Now Regular Users, Research Shows. (Cleveland Plain Dealer)

The (6/20) A study led by the University of California-San Diego and published in JAMA Internal Medicine found that marijuana use among U.S. seniors aged 65 and older has increased, with 7% reporting current use in 2023, up from under 5% in 2021, driven by its use for managing chronic conditions like diabetes and high blood pressure; Joseph J. Palamar, MPH, PhD, associate professor, Department of Population Health, said, “It shouldn’t be surprising that use is becoming increasingly more common among people who live in states that allow medical cannabis, which could be due to increased availability or social acceptability.”

Dermatologist-Approved Tips For Choosing A Safe And Effective Sunscreen. (Verywell Health)

(6/20) Jennifer A. Stein, MD, PhD, professor, the Ronald O. Perelman Department of Dermatology, Perlmutter Cancer Center, associate vice chair, Faculty Practice Group, Department of Dermatology, recommended mineral sunscreens for those concerned about safety, noting that “both mineral and chemical sunscreens can protect your skin, but chemical sunscreens may be absorbed into the bloodstream when applied repeatedly to large areas of your body,” and advised looking for products containing titanium dioxide or zinc oxide to ensure protection against UV rays.

Avoiding The COVID Shot Talk? Here’s What To Do. (Medscape)

(6/23)* Conversations about COVID vaccines between physicians and patients are becoming less frequent due to factors such as short visit times, shifting clinical priorities, and “COVID exhaustion,” according to Art Caplan, PhD, the Drs. William F. and Virginia Connolly Mitty Professor of Bioethics, Department of Population Health, Division of Medical Ethics, who said, “There is a feeling that everybody who’s going to get COVID either got it or got vaccinated or doesn’t want [the shot].”

News from �����о��� Langone Health—Long Island

What The Latest GLP-1 Guidelines Could Mean For Midlife Women. (Flowspace)

(6/20) The American College of Cardiology has released new guidance recommending the use of weight-loss drugs, such as GLP-1 and GIP receptor agonists, as a strategy to reduce cardiovascular risk in overweight individuals, shifting from prior guidelines that prioritized lifestyle changes; Shaline Rao, MD, assistant professor, Department of Medicine, the Leon H. Charney Division of Cardiology, chief, Division of Cardiology, chief and vice chair, Operations of Medicine, �����о��� Langone Hospital—Long Island, said, “This also means now there will be shared decision making between the patient and physician and customization of the plan to their individual goals.”