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News from ������� Langone Health

Surgery Leads To 5 Times Greater Weight Loss Than Ozempic, New Research Reveals. (Best Life)

(6/18) New research presented at the American Society for Metabolic and Bariatric Surgery 2025 Annual Scientific Meeting indicates that metabolic and bariatric surgeries, such as sleeve gastrectomy and gastric bypass, result in five times greater weight loss compared to GLP-1 receptor agonists like semaglutide and tirzepatide, according to a study by �����о��� Langone Health and NYC Health + Hospitals; Avery Brown, MD, general surgery resident, Department of Surgery Education, said, “GLP-1 patients may need to adjust their expectations, adhere more closely to treatment or opt for metabolic and bariatric surgery to achieve desired results.” Karan R. Chhabra, MD, assistant professor, Departments of Surgery and Population Health, added, “In future studies we will aim to identify what healthcare providers can do to optimize GLP-1 outcomes, identify which patients are better treated with bariatric surgery versus GLP-1s, and determine the role out-of-pocket costs play in treatment success.”

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Telisotuzumab Vedotin Maintains Efficacy Across Key Subgroups In Pretreated NSCLC With c-MET Overexpression. (OncLive)

(6/19) “Data from an analysis of the phase 2 LUMINOSITY trial (NCT03539536) demonstrated that telisotuzumab vedotin-tllv (Emrelis) was active in patients with c-MET protein–overexpressing non–small cell lung cancer (NSCLC) regardless of prior therapy, further supporting the agent’s role in the second-line setting, according to Joshua K. Sabari, MD, assistant professor, Department of Medicine, Division of Hematology and Medical Oncology, Perlmutter Cancer.

Swallowing Risk: The Hidden Dangers 7 Of America’s Most Popular Supplements. (Genetic Literacy Project)

(6/19) “Three in four Americans take at least one dietary supplement, according to the U.S. Food and Drug Administration,” but Julia Adamian, MD, clinical professor, Department of Medicine, Division of General Internal Medicine and Clinical Innovation, section chief, General Internal Medicine and Clinical Innovation, said, “What makes some dangerous is the fact that most people think they cannot hurt and are always safe, so the suspicion is that a large amount of patients do not mention it to their doctor.”

“Jumping Genes” Found Hijacking Cell Division To Rewrite Human DNA. (SciTech Daily)

(6/18) A study led by researchers at �����о��� Langone Health and the Munich Gene Center at Ludwig-Maximilians-Universität München in Germany “revealed specifically that LINE-1 can only bind to DNA when ORF1p – which can bind to RNA, DNA, and itself in linked copies called multimers – accumulates into clusters of hundreds of molecules called condensates,” with senior study author Liam J. Holt, PhD, associate professor, Department of Biochemistry and Molecular Pharmacology, saying, “Our study provides crucial insight into how a genetic element that has come to make up a large part of human DNA can successfully invade the nucleus to copy itself. These findings on the precise mechanisms behind LINE-1 insertion lay the foundations for the design of future therapies to prevent LINE-1 replication.”

RevelAi Health: $3.1 Million Seed Funding Raised For Scaling AI Care Coordination. (Pulse 2.0)

The (6/19) RevelAi Health, a conversational AI platform for musculoskeletal care, announced a $3.1 million seed round to enhance electronic health record and practice-management integrations, expand AI-collected outcome surveys and risk pathways, and accelerate collaborations with health systems Joseph D. Zuckerman, MD, the Walter A.L. Thompson Professor of Orthopedic Surgery, and chair, Department of Orthopedic Surgery, said, “From my perspective, conversational AI is essential for succeeding in value-based mandates like the Transforming Episode Accountability Model.”

Age-Friendly ERs Are Good Medicine. (Youngstown (OH) Vindicator)

The (6/20) Ula Hwang, MD, MPH, professor, the Ronald O. Perelman Department of Emergency Medicine, and Population Health, highlighted the importance of age-friendly emergency care, noting that older adults account for 21% of emergency department visits annually, according to 2022 CDC data, and emphasized the need for specialized protocols and physical adaptations to address risks such as delirium and falls, while also considering cognitive and medication evaluations to tailor care to older patients’ unique needs.

The Surprising Truth About How Long You Should Hold A Plank. (Prevention Magazine)

(6/20) Heather A. Milton, MS, RCEP, CSCS, exercise physiologist supervisor, ������� Langone Sports Performance Center, said that planks are effective for engaging core muscles and supporting spinal stability, recommending starting with a duration that maintains proper form and gradually increasing by five to 10 seconds weekly, aiming for 40 to 60 seconds, while incorporating modifications like knee planks or progressions such as lifting a limb; Milton further advised planking two to three times weekly, integrating them into a comprehensive workout routine, and considering them as a warm-up to prepare core muscles for more strenuous exercises like squats and deadlifts.

Vocal Cord Injuries And High Temperatures Suppressing Appetite. (WNYW-TV New York)

(6/19) Purvi S. Parikh, MD, clinical assistant professor, Department of Pediatrics, Division of Pediatric Allergy & Immunology, and Department of Medicine, Division of Infectious Diseases, Allergy and Immunology, discussed the impact of vocal cord injuries on Broadway performers; she also addressed how high temperatures can suppress appetite by reducing the need to burn calories to raise body temperature and by lowering levels of the hunger hormone ghrelin, leading people to avoid spicy or heavy foods in the summer.

News from �����о��� Langone Health—Long Island

Preparing For Oncology Board Certification, Career Transitions, And Combating Burnout. (Cancer Network)

(6/18 Marc J. Braunstein, MD, PhD, associate professor, Department of Medicine, Division of Hematology and Medical Oncology, Perlmutter Cancer Center—Long Island, developed a curriculum to aid fellows in their transition to attending physicians, covering topics like networking and clinical trials, while maintaining an open-door policy for graduates.