About Me
As a psychiatrist at 秘密研究所 Langone, I am dedicated to advancing the field of psychedelic-assisted therapy. My approach to patient care is deeply rooted in understanding psychiatric disorders through a multifaceted lens that includes biological, social, psychological, and psychospiritual dimensions. This comprehensive perspective guides my commitment to providing holistic care, ensuring that each individual鈥檚 unique experiences and needs are addressed.
I specialize in psychedelic-assisted therapy, focusing on conditions such as alcohol use disorder and major depressive disorder. My work in this area is driven by early data suggesting that these treatments can offer more holistic solutions to clinical concerns. At 秘密研究所 Langone鈥檚 Center for Psychedelic Medicine (CPM), I am involved in various research studies, acting as a co-investigator, study therapist, and clinical supervisor. My goal is to integrate patients鈥 lived experiences into the therapeutic process, aiming to understand and ease their symptoms through innovative and emerging treatments.
Throughout my career, I have accumulated extensive experience in the practice of psychedelic therapy within the research setting. My work includes Phase 2 trials of psilocybin-assisted therapy and other psychedelic interventions for a variety of clinical indications. I am committed to fostering clinical and intellectual excellence in psychedelic psychiatry, both within the CPM and the broader community. My efforts are motivated by a desire to support patients and train the next generation of mental health professionals.
My journey into psychiatry was shaped by a diverse academic background and a passion for multidisciplinary inquiry. I began my undergraduate studies in the Great Books program at St. John鈥檚 College, exploring philosophy, literature, mathematics, science, and the arts. This eclectic foundation led me to pursue scientific research at the National Institute of Mental Health (NIMH) and later, an MD/PhD program at UCLA. After completing my PhD in neuroscience, I returned to medical school with a vision of integrating science, service, and the humanities. This vision ultimately led me to psychiatry and psychedelic research, where I strive to advance the rigor, ethics, and understanding of these treatments in service of patients, participants, and the public.
Credentials
Positions
- Clinical Associate Professor,
- Director, Clinical Training Center for Psychedeli
Board Certifications
- American Board of Psychiatry & Neurology - Psychiatry, 2019
Education and Training
- Residency, 秘密研究所 School of Medicine, Psychiatry, 2019
- MD from University of California, Los Angeles, 2015
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Insurance Plans Accepted
Please call the office for information about accepted insurance plans.
Kelley O'Donnell, MD does not accept insurance.
Research My Research
Interests
psychedelic, psilocybin, MDMA, psychedelic-assisted therapy, psychedelic ethics
Research Summary
With a family history of mental illness and addiction, I was long aware the these psychiatric disorders emerge at the interface of biological, social, psychological, and psychospiritual dimensions of experience. For that reason, I became interested in psychedelic-assisted therapy research, given early data suggesting that psychedelic treatments might address clinical concerns in a holistic way.
I have been involved in psychedelic clinical research at 秘密研究所 Langone since I began residency training on the research track, working with Drs. Michael Bogenschutz and Steve Ross on Phase 2 trials of psilocybin-assisted therapy
for alcohol use disorder and major depressive disorder. Since then, I鈥檝e accumulated extensive experience in the practice of psychedelic therapy in the research setting, working on studies of psychedelic interventions for a
variety of clinical indications. I seek to understand and develop novel and holistic treatments for mental health concerns. To that end, I鈥檝e acted as a co-investigator, study physician, trainer, clinical supervisor, and adherence rater for many clinical trials of psychedelic treatments for various psychedelic trials. My efforts in the research setting are motivated by a desire to support the patients who are suffering, and the trainees who hope to serve them. Given my holistic orientation, I have a particular interest in the role of psychotherapy and the therapeutic relationship in the efficacy of these emerging treatments.
Clinical Trials and Research Studies
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A Phase 2b Randomized Double-blind Placebo-controlled Multi-center Study of the Effects of Psilocybin-assisted Psychotherapy on Psychiatric and Existential Distress in Advanced Cancer
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5-HT2A Agonist Psilocybin in the Treatment of Tobacco Use Disorder
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A Phase 3 Randomized Double-Blind Multicenter Study to Evaluate the Efficacy Safety and Tolerability of Psilocybin in Adults with Major Depressive Disorder
Publications
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Bogenschutz, Michael P; Ross, Stephen; Bhatt, Snehal; Baron, Tara; Forcehimes, Alyssa A; Laska, Eugene; Mennenga, Sarah E; O'Donnell, Kelley; Owens, Lindsey T; Podrebarac, Samantha; Rotrosen, John; Tonigan, J Scott; Worth, Lindsay
JAMA psychiatry. 2022 Oct 01; 79(10):953-962
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O'Donnell, Kelley C; Okano, Lauren; Alpert, Michael; Nicholas, Christopher R; Thomas, Chantelle; Poulter, Bruce; Mithoefer, Ann; Mithoefer, Michael; Ot'alora G, Marcela
Frontiers in psychology. 2024 Oct ; 15:1427531
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O'Donnell, Kelley C.; Roberts, Daniel E; Ching, Terence H.W.; Glick, Gianni; Goldway, Noam; Gukasyan, Natalie; Hokansen, Jamila; Kelmendi, Benjamin; Ross, Stephen; Yaden, Mary E.; Pittenger,Christopher
Psychedelic medicine (New Rochelle, N.Y.). 2023;